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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1d7f609f6be7250236ea78d805754bd3078f46ab6aea4f4745db97ae3f9c0b' 
  AND token = '+VZXqxmPlJiRawG8IJwLH7Ub+TO6N4JZSJhqqS0tuV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}