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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c08f7030032d0a188aa5d429004b44cb16b597a756738c9c2edc2fcb899673f5' 
  AND token = '/MMxt5F+fpY4DmJ2vIbH+MiOPEi/3Cd/Yra07RlADLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}