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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6503dc58d87be60aef50b98e6af682c015a716dee2eb00cdd7aac1c35d4d414d' 
  AND token = 'poNbtPKmAgH6+tVscJvqOUM/9wWw2KmqGDsSZ2uJs5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}