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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc88678b553551717041f8d717181c7ec10f4ab3e52b38d66063ea8ad149bf0d' 
  AND token = 'zzB/fNQ5rHKTRnWzUrl826VzNI+CYzalxk5W/wrNTcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}