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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8137f988f17736ae991ab14a66c49012261f346a607e0f3d34c38dba21163274' 
  AND token = 'Q7JfzPqB6+PT+wULDAiuw+1HIrn1CPokOTAaVfiSNc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}