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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4576eea67d9c1321fd373456a9d1c1c34c2280b664177ed648ae3764005ab6a' 
  AND token = 'q+S2/emP4I1l57B/BP+9jUf3IvyzrDll3iQQ+BtHhcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}