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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b8449fe9a629dde96d319f27236ef3dd9419c21c1b4f5bc1750fe8ba7e104f' 
  AND token = 'cY0YOQlbICco3OkxCyLX/BixjPa4YlU498n3QyNIqEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}