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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bbd9c65eada783b76520ea6137158fa0bf27240e2a4042ace1b57b1dabbb6f7' 
  AND token = '4HPL+di8DDzdMOv5A5GatSSTGiEfXWN1SAzxLNQebI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}