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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7f550387e9632a359bff1e52fe1d103ad7ba4049dbe61675db3caf4b729fc3b' 
  AND token = 'dTq0b9kOiKwPI0+GD6m9RZ9kshQ0WTwrjIn9W5Gx2/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}