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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd033617c4268d6af43086954e3314788c3d2e4738541d09ba15f518fadff86df' 
  AND token = 'D4xf2wRcUB3aaAj0QdO2qrjqfw4jb28T/DUHVnshI3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}