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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e40eec52f21260d0641fa36cd455cdfcca8c59136bd3f2c7d7d869d3dbe060' 
  AND token = '5yPdHtbOwNVGCXZWsX6HtBOToPeFzQJK1pzik+2Xj5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}