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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8152100e82b2b271bd6c9bd13d052464d3bec01b0b947bdc507776b89496895' 
  AND token = 'ai0clA0zeVnqbOVmtw4ZtVrSqDYm9z+xFbdRSfkxESc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}