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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08f5183ce3cab372f859dac44edeb30623a13a785731aec3ddda04a187b5727a' 
  AND token = 'U2D1OehWMxLzkczxCa6fLIvlBL7n3KsO4vFLvl/XTes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}