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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80137f0b7a8873f68900ecbfc65c038a8513c3210dd1412a8e193a90bc8e502' 
  AND token = '8RYGUZ+sQ5wzLezaUgNWyC//tmRIoNH/9hfgfkMD1EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}