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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cb50a4f829a9f8e6bf06756ac4c2612c8d81fdb26caa157483d1059ac9246ac' 
  AND token = '2MSq7FNmaidxKQbIuEhexVyt+vwgXv0EaNNMzM0bDoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}