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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '660344864e8c44e1ad9ecc9f8693f249eb9365197d102a047f8d996d1aa82a2b' 
  AND token = 'dB4zLyM6jFgYTRf6lEh8HnwHRHvD9FOSUZk/2p3wYAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}