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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1511ad3e66e72bd7c571c48433220aeff7b9393372be4ed54448f943c89ad040' 
  AND token = 'Jq4M153iJ6b0/UoAStcNgkZCw5xp07uS9Vp3OEGCNSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}