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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6644f8bd247f146a145f604e5e2a5a33d66774f7e4c468819999750fab9425' 
  AND token = '7FJ71vP5HsrcMAIbwKij3T2P5lRRX95rOL3yUXHrzmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}