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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32a41f61908e9225a8709d3020a9eeb61b32739e92acbfd92157e94d3c01f995' 
  AND token = 'xBK61cnegWI2zCco61FlG+HmFPOT7SMv1XP3Z0nUaiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}