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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2629c7555f16325448641d41dd888882e47f94e790eea30e03811c8b402b1992' 
  AND token = 'UGaTtB9PqoV1Ig9C6EBSVDJoRgCvhua2DYN2jkTR270=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}