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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8861d79677085287fb1eabc5376184e95bae74728ed1f851ede94be2ab1afd61' 
  AND token = '5ZnlcUEqjhigRjzYixvjne8sOqPIXC1uNKrGy9Nm6TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}