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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b3df47226379d01883018167f485f0ea722c10d9e0c3ee9f59851d57831b12' 
  AND token = 'DrbjJIbps+d0rVvt5OTZMwAkyyOpWZYXbaZ2SB0B4Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}