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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1466a626dd7f7dbc5e8723f24ad1c0c14ab25dc1d51001cfac24c16d8d136c34' 
  AND token = 'W6GIk2JTO7Lsidh6gxpODOBvJze52Eud2AQq5ET+WhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}