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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541ede3fb225600fb32ab616207c933295f961875e12ce3c39a84b3b7c6b8a0d' 
  AND token = 'v27na9Vf34iNwHLLS9olVOyinOLuTNDryaGjyqGYGMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}