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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45083a7322574dfd5d66329ff717247683f65a8c3d5ccab902741a97453f7525' 
  AND token = 'lM1Ay0muDmCWQdyefHEP/SA4pRZeoGHygHHgs16eK3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}