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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a68a857d75339fca8bee071355c7b0b36a1b33874296fdb17610097e6035ac' 
  AND token = 'Y2E3yUbmbue9mJpHn32y/b+r86W67Fp/HEJe7tIScYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}