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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f772ff4aec8b2e9378e5425978233d351b0cdd9ee7a73e73eff968de93dbcf' 
  AND token = 'e7wW4CMos1e1GYehSUAbQJXz7COqR+r1wUsUPsAL6Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}