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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '349b1ed06a63b01e5236616c4de9ab99207add1eebe8ded8857e04efb0e198bb' 
  AND token = '0mSfOaCPxAfgkoenTTHUq2d7hhYZ4Os3W/VTB00qNEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}