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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9af5e77c134d713908d13b5586c9f7be06d0d5d243b9dea55b3f00220dd8ab5a' 
  AND token = '+fxtjIV9PXPWZK0R+C4ESLnB4xrw7gcF1oHNeC2I3gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}