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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b2f3db9bc0a0d3fbc3fda70419d31ddf60ab3b46d3074100d3ac2376b50a9f' 
  AND token = 'HM/8EReQfRRoYJ96HPnLg1FA6MZAvP1uLpv1lDLO9QU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}