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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8beeaa942c0f329d60f320bf3349261c1b5bd02be9592d60e64d43b133f0668a' 
  AND token = 'A+wQS2LgA2i85UezC+Z75PGsstEeK9fRfFTBWMQFULk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}