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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f5df9f4518ecd6ae5444254ce0e840163cfe3770942df0a85be1ed1fad0e8a' 
  AND token = 'igyn6oDyEev8sarbbDH4pEumqhLFy4fvFAtIKVEGbD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}