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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd6ec30b0a35996880d75c87a12c00870b7b4ca12c143d03dd8c2f65e314b1d' 
  AND token = 'SK3Jq0hOzGdnSxrSqRdJH3zoLR6TWoXsk3yrUT0Etvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}