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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e07b98d2732556ba1a5b9c46249dbe3d64bad723d26a04bcffa41019bb8bfaa5' 
  AND token = 'Tw1gH+ctvkiLw7HqLn6+0eFtCVIBorLPcwhSy6hh0PU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}