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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa1de5a73a499a8e561498a4613fd25ae4efbb50296939a1a093bac75c1938f' 
  AND token = 'vtNYieUxnxEi3gxm0Lmb1kviAPLGFY1nbP+uXA2gjuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}