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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '283bacf5bb81f16d3b9c519b1b32d835cfe1f5e81cfc8b8f312b9593bf3b553e' 
  AND token = '+cFdS+09lCtXYkH+hSIE8521XtSK5pfMdrRcAaizatM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}