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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cd1ebadbee0ea3f38cf1f3618d78ec15bd2a57f2c04165f062d0279843f78f' 
  AND token = 'LQLdZZ3movI0khlEV2zYMR5VV08xM+cUrMnO5+XfsiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}