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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1ada83d97e758d453db672b181cdb7a27a786bef6393f598cd7a24521a5dab0' 
  AND token = 'ZR+q1ERRqkY7k5BQY/hh/BR8LoQaaAddtmyYerQQuJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}