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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6116b73378e2c45d5698b3353c9fbf1a55f77f3cdf45f9ebc0123c5b70513dc3' 
  AND token = 'H0dKJkXzu4qAoYtVf11sFPrUNlvcrcQBA2UP6wlrD1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}