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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e929066324a00cb289f39f973acd0abb0913a996b73bbc5ecbb9014dab2812' 
  AND token = 'nxRYuPw5UUEVwduiys8wn+3rbs2JHo6VrbZwfhByrFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}