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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '915841ddc919cdf3a1c289fdcb31e0ae6ccae77480f54dd3861f7c728ce127f4' 
  AND token = 'n6/xpEN8Aks6Ln83CC5v5iy4Ztx17QPRhguJIuywv2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}