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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c0c5c56c18c5a84e672014eadf0d9e01800e9473842529911149b25cc38255' 
  AND token = '/Go0h5RL6KAKA8ziVP2EwmsCxKQkeGam1ExxLEs4fI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}