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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de74851775d874b2a255a816101ce24e9e3d2ec84df3a11dc18ee88f06c6ae04' 
  AND token = '81AsuZAdYZ/j5s4DRYHgg1BzWKll1dpSgbwZej7Atws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}