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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f248a2a5701a8b9c2167e545b61f8a99f702fa0dfb12a055be1d0450814d62cf' 
  AND token = 'bsMY0BEm/AZeyuomGk+A0hDr5ToLkqxJN7Ws2ZfHLVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}