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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3329c84a9c5b311d971d48f89217d8d6f73c0697ac95043610db04f5ebb9da' 
  AND token = 'Mj26PiFtDC/3w/DBYPwEZ7FBRPehoo514RmDRXDQ2GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}