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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8371076d89397313de6c0342817d14863b2d49aabd1fb34fa9b7ff1a84d8069f' 
  AND token = '8D7lML5NKxmhSbFH117vi3Iqq6A4Dx/LVrnSsXNi65g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}