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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441c4d8ce3c726157508d0ab1ceeddb416770f550be01ce48bc9c57f81a87200' 
  AND token = 'IaR8WV/UKNRO+FlvvVyRiFY5G4shE34hSaplhJJSptA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}