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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '771be210e8ec4f7dac421eb3fb267828472fc88dda2ec4d9c0fca3f421a121a2' 
  AND token = 'LNofdKdMpDxrr+fIbOAwKrd4Hjxa3ASFlEx0S+lmYOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}