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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '531e1dfc950aab5e76db7a850d3f63c88f879a489b13eec125fca272ea4dbe44' 
  AND token = 'dJWE4sTD54wgOSPahIa8/HfJEFw3lAezoFHxRpsbbp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}