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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f6ac2f360a3e2996d98794523902c55c9fce2a6c9c0858782d03270c60303f0' 
  AND token = 's4W0L/VaUtj2oKqAWU+NfAsvCkP7155x7Aag27/sLL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}